This topic is managed by the Multiplicity
Advisory Board (
Alex
Dmitrienko).
This page includes links to articles on software
implementation of multiple testing procedures in pre-clinical
and clinical applications.
If you would like to contribute to the Code
Depot project, the Multiplicity Advisory Board encourages you
to post relevant information in this discussion thread in the
BioPharmNet forum.
Tree gatekeeping procedures serve as an
extension of serial and parallel gatekeeping procedures and can
be used in clinical trials with multi-dimensional objectives (multiple
endpoints, doses, tests, etc) and clinical trials with logical
restrictions.