Category: Clinical trial simulations.
Mediana Designer is a free Windows-based software tool that supports traditional and simulation-based power/sample size calculations in fixed-sample and group-sequential trials.
The current version of Mediana Designer comes with the following three applications:
- Application 1 (Analytical calculations in fixed-sample trials): This application supports analytical evaluation of operating characteristics in clinical trials with a fixed-sample design.
- Application 2 (Simulation-based calculations in fixed-sample trials): This application implements the simulation-based Clinical Scenario Evaluation approach in clinical trials with a fixed-sample design.
- Application 3 (Analytical and simulation-based calculations in group-sequential trials): This application implements analytical and simulation-based evaluation of operating characteristics in clinical trials that employ group-sequential designs with several decision points.
Other applications will be added in the future.
Download Mediana Designer
Download a ZIP archive with a test version of Mediana Designer and required libraries. The current test version is 0.2.
After downloading the archive, extract the files and place them in the same folder. Note that Mediana Designer relies on a stand-alone executable file (MedianaDesigner.exe) and does not require installation. Double click on MedianaDesigner.exe to start the software tool.
Mediana Designer project files
Project files based on multiple case studies have been created to demonstrate how Mediana Designer can be used to perform power and sample size calculations in Phase II and Phase III clinical trials.
Mediana Designer reports and slide sets
An important feature of Mediana Designer is that it automatically generates reports (Microsoft Word documents) and slide sets (Microsoft PowerPoint presentations) with a detailed summary of operating characteristics of the selected clinical trial.
Download all Mediana Designer reports and slide sets for the case studies in a single ZIP archive.