Category: Subgroup analysis.
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Software for subgroup identification
R package SIDES implementing the regular SIDES method (Subgroup Identification Based on Differential Effect Search) based on Lipkovich et al. (2011) [last update: October 04, 2016]. The package is maintained by Marie-Karelle Riviere (firstname.lastname@example.org).
Download the SIDESxl package (an Excel add-in) which implements the regular SIDES and SIDEScreen methods [last update: March 25, 2016]. The package is maintained by Ilya Lipkovich (email@example.com).
Download the R functions, C++ functions (sides64.dll), and examples for the regular SIDES (Lipkovich et al., 2011) and SIDEScreen (Lipkovich and Dmitrienko, 2014) methods [last update: December 13, 2016]. The functions and examples are provided by Ilya Lipkovich (firstname.lastname@example.org).
Interaction Trees method
Download the R functions and examples for the Interaction Trees method [last update: Dec 30, 2014]. The functions and examples are provided by Xiaogang Su (Xiaogang Su’s site). Download the R code for the Interaction Trees method [last update: Dec 30, 2014].
Virtual Twins method
Download the R code for the Virtual Twins method [last update: Dec 30, 2014]. The code is provided by Jared Foster (email@example.com).
R package aVirtualTwins that implements an adaptation of the Virtual Twins method by Foster et al. (2011)
GUIDE package for classification and regression trees now includes methods for subgroup identification. The GUIDE package is maintained by Wei-Yin Loh (Wei-Yin Loh’s site). For more information on the subgroup identification features, see Section 5.10 of the GUIDE User Manual [last update: February 11, 2015] and paper by Wei-Yin Loh, Xu He and Michael Man.
Download the R functions for the Bayesian two-stage Lasso strategy for biomarker selection for time-to-event endpoints [last update: December 16, 2014]. The code is provided by Xuemin Gu (firstname.lastname@example.org). Reference: Gu, Yin and Lee (2013).
Model-based Recursive Partitioning
R partykit package: A Toolkit for Recursive Partytioning, which can perform subgroup analyses using the functions lmtree(), glmtree() (or more generally, mob()) and ctree()). See examples of subgroup analysis in Seibold et al. (2015) and Seibold et al. (2016)